All publication

2025

• Cell shape modulates mitotic spindle positioning forces via intracellular hydrodynamics. Xie
  J, Najafi J, Nommick A, Lederer L, Salle J, Dmitrieff S, Lacroix B, Dumont J, Minc N. Curr Biol.
  2025 Jan 20;35(2):413-421.e6. doi: 10.1016/j.cub.2024.11.055. Epub 2025 Jan 3. PMID:
  39755120.

2024

• Germ fate determinants protect germ precursor cell division by reducing septin and anillin
  levels at the cell division plane. Connors CQ, Mauro MS, Wiles JT, Countryman AD, Martin SL,
  Lacroix B, Shirasu-Hiza M, Dumont J, Kasza KE, Davies TR, Canman JC. Mol Biol Cell. 2024
  Jul 1;35(7):ar94. doi: 10.1091/mbc.E24-02-0096-T. Epub 2024 May 2. PMID: 38696255;
  PMCID: PMC11244169.
• Measuring Mitotic Spindle and Microtubule Dynamics in Marine Embryos and Non-model
  Organisms. Chenevert J, Robert MLV, Sallé J, Cacchia S, Lorca T, Castro A, McDougall A, Minc
  N, Castagnetti S, Dumont J, Lacroix B. Methods Mol Biol. 2024;2740:187-210. PMID:
  38393477
• Cell Cycle Control: Methods and Protocols. Castro A & Lacroix B. Editors Part of the book
  series: Methods in Molecular Biology (Springer Protocols, Humana Press. 2024. (Book
  Edition)Increases in cyclin A/Cdk activity and in PP2A-B55 inhibition by FAM122A are key mitosis-

inducing events. Lacroix B, Vigneron S, Labbé JC, Pintard L, Lionne C, Labesse G, Castro A,
Lorca T. EMBO J. 2024 Mar;43(6):993-1014. PMID: 38378890

2023

• Synergistic stabilization of microtubules by BUB-1, HCP-1 and CLS-2 controls microtubule

pausing and meiotic spindle assembly. Macaisne N, Bellutti L, Laband K, Edwards F, Pitayu-
Nugroho L, Gervais A, Ganeswaran T, Geoffroy H, Maton G, Canman JC, Lacroix B, Dumont J.

Elife. 2023 Feb 17;12:e82579. PMID: 36799894

• Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based
  p21 Degradation Screen. Pelletier B, Duhamel S, Tambutet G, Jarvis S, Cléroux P, David M,
  Tanguay PL, Voisin L, James C, Lavoie R, Gareau Y, Flynn-Robitaille J, Lorca T, Ruel R, Marinier
  A, Meloche S. ACS Chem Biol. 2023 May 19;18(5):1039-1046. doi: 10.1021/
  acschembio.2c00909. Epub 2023 Apr 25. PMID: 37097827.

2022

• Structural, enzymatic and spatiotemporal regulation of PP2A-B55 phosphatase in the control
  of mitosis. Lacroix B, Lorca T, Castro A. Front Cell Dev Biol. 2022 Aug 29;10:967909. doi:
  10.3389/fcell.2022.967909. PMID: 36105360; PMCID: PMC9465306.
• Spatial and Temporal Scaling of Microtubules and Mitotic Spindles. Lacroix B, Dumont J.
  Cells. 2022 Jan 12;11(2):248. doi: 10.3390/cells11020248. PMID: 35053364; PMCID:
  PMC8774166.
• Structural organization and dynamics of FCHo2 docking on membranes. El Alaoui F, Casuso
  I, Sanchez-Fuentes D, Arpin-Andre C, Rathar R, Baecker V, Castro A, Lorca T, Viaud J,
  Vassilopoulos S, Carretero-Genevrier A, Picas L. Elife. 2022 Jan 19;11:e73156. PMID:
  35044298
• PP2A-B55: substrates and regulators in the control of cellular functions. Amin P, Awal S,
  Vigneron S, Roque S, Mechali F, Labbé JC, Lorca T, Castro A. Oncogene. 2022 Jan;41(1):1-14.
  (Review article) PMID: 34686773

2021

• The study of the determinants controlling Arpp19 phosphatase-inhibitory activity reveals an
  Arpp19/PP2A-B55 feedback loop. Labbé JC, Vigneron S, Méchal i F, Robert P, Roque S,
  Genoud C, Goguet-Rubio P, Barthe P, Labesse G, Cohen-Gonsaud M, Castro A, Lorca T. Nat
  Commun. 2021, 12(1):3565. PMID: 34117214
• Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote
  mitotic entry. Tavernier N, Thomas Y, Vigneron S, Maisonneuve P, Orlicky S, Mader P, Regmi
  SG, Van Hove L, Levinson NM, Gasmi-Seabrook G, Joly N, Poteau M, Velez-Aguilera G, Gavet
  O, Castro A, Dasso M, Lorca T, Sicheri F, Pintard L. Nat Commun. 2021, 12(1):1899. PMID:
  33771996

2020

• In Vitro Reconstitution of Dynein Force Exertion in a Bulk Viscous Medium. Palenzuela H,
  Lacroix B, Sallé J, Minami K, Shima T, Jegou A, Romet-Lemonne G, Minc N. Curr Biol. 2020
  Nov 16;30(22):4534-4540.e7. doi: 10.1016/j.cub.2020.08.078. Epub 2020 Sep 17. PMID:
  32946749.
• PP2A-B55 Holoenzyme Regulation and Cancer. Perrine Goguet-Rubio, Priya Amin, Sushil
  Awal, Suzanne Vigneron, Sophie Charrasse, Francisca Mechali, Jean Claude Labbé, Thierry
  Lorca, Anna Castro. Biomolecules. 2020, 10(11):1586. (Review article). PMID: 33266510

2019

• Arpp19 and ENSA, two PP2A-B55 phosphatase inhibitors that differentially control the cell
cycle. Hached K, Goguet-Rubio P, Charrasse S, Lorca T, Castro A. Med Sci (Paris). 2019,
35(6-7):504-506. (Review article). PMID: 30626720

• Nuclear import of Xenopus egg extract components into cultured cells for reprogramming
  purposes: a case study on goldfish fin cells. Chênais N, Lorca T, Morin N, Guillet B, Rime H, Le
  Bail PY, Labbé C. Sci Rep. 2019, 9(1):2861. PMID: 30814557
• ENSA and ARPP19 differentially control cell cycle progression and development. Hached K,
  Goguet P, Charrasse S, Vigneron S, Sacristan MP, Lorca T, Castro A. J Cell Biol. 2019 Feb
  4;218(2):541-558. PMID: 30626720